AFnord: No, Desura is not like Steam, there is one pretty major difference between the two.
With Steam, (almost) all games that you download will have to be played through steam, with steam active at all time. With Desura, that is not the case, the games are not linked to Desura, and you can run them on their own, without starting Desura. With Steam, the client is a form of DRM, while with Desura, the client is just there for convenience (and they are working on direct download from the site for all games, so you won't have to use the client).
Cool!, thanks for the clarification. Maybe I will create a Desura account soon. One question though, do you still need the Desura client installed in your computer to buy and install the games?