That is really worked! Thank you so much! :D

I was in a particularly "debuggy" mood (given how obnoxious this one laptop I'm fixing is being!) and thought to myself "how can I make this more convenient?" Step 1: Don't use compatibility mode for the actual game. Step 2: Use this PowerShell script I made.

mount-diskimage -imagepath "C:\Program Files (x86)\Virtual Springfield\Virtual Springfield.iso"
start-process "C:\Program Files (x86)\Virtual Springfield\VIRTUAL.EXE" -wait
dismount-diskimage -imagepath "C:\Program Files (x86)\Virtual Springfield\Virtual Springfield.iso"
exit

Because Windows is weird about running PowerShell scripts, I used this batch file to run my script.

powershell -executionpolicy remotesigned -file "C:\Program Files (x86)\Virtual Springfield\Launcher.ps1"

Of course, if you have a CD (or a crack I couldn't find) there's no need for this. And it goes without saying to point to your own install and iso pathnames, you lummox. :P