Ask this to thread opener then?

Me.

Psygnosis' PC titles would be awesome, notably Wipeout XL/2097 and the Discworld games. Wipeout seems impossible to get to work with my PC.

I'd love to see Terminator: Future Shock and Skynet, perhaps the best games to use the Terminator license. They are first person shooters done by Bethesda, the makers of Fallout 3 and the Elder Scrolls games / Oblivion.
When they were working on Fallout 3 everyone was skeptical whether they could go from doing a swords and sworcery RPG thing to a post-apocalyptic shooter game, I was pretty confident they could because they already had. Terminator Future Shock and its sequel/expansion Skynet are AWESOME.
Made around the same time as Duke Nukem 3D and Quake, yet significantly better looking, and with all kinds of amazing features like drivable vehicles with gun turrets (both cars and aircraft!), true 3D levels and true 3D enemies... It's like Half-LIfe 2 and Fallout 3 and Stalker: Shadow of Chernobyl if you reversed engineered them into the Quake engine. (And they didn't even use Quake engine, they created their own engine.)
One of the cool things is that although the levels and enemies were 3D, the guns on your screen used 2D sprites, allowing them to be much more detailed and interesting looking than the tube-shaped guns of Quake. (Back then an interesting-looking gun model would have used too many polyguns.) I loved the blaster with working night vision scope - it had a screen which had a miniture version of whatever you were looking at, highlighted in green night vision.
Yes, yes please. The Crusader games are bloody awesome.

This. PLEASE.
And Terminator games would be badass, Rampage wasn't that bad either. Bit hard to navigate tho. Would still like Bethesda to do another Terminator game to try and redeem the series again, none of this current-movie license bs.

Age of Wonders
You don't know age of Wonders ? Well, let me explain to you.
Imagine Heroes of Might and Magic. Fair game, eh ? Now imagine HoMM with research. Ah ! Sounds nice. Now HoMM with much more tactical combat (hide behing trees to fire your bows and try to get the higher grounds) ? Looks cool ?
Those are not even the main features.
The main feature of the game is the strategic map : largely modifiable. You can rise the level of water, froze huge chunks to slow the opponents down, create forest for your elves (did I mention that armies with elves are invisible in Forest ?), destroy enemy strongholds, mills, mines or mana sources - but beware or angering the Gods. Fly above the mountains with your flying troops, or just walk through if you have dwarves. You cannot rush directly to the enemy capital because once you are in this territory, he WILL wreck your army with "spells", so you want to prefer a quick grab to a huge attack. But will you attack through the mountain, going slowly but surprising him ? Land from the water, but being exposed to have your boats sunk with your troops inside ? Dig (literally) your way through the underground ? Or go the main route through the forest, hoping he hid nothing there ? So much strategy, decent IA, this is definitly one of the best game around.

Re-Volt!
Classic racing game with simulated radio-control vehicles set loose in supermarkets and other non-standard environments. Semi-cartoonish graphics, twitchy responses (as you would expect at this scale), special "weapons"... Generally just great mayhem.
Problem is, many people seem to have issues running Re-Volt under Vista, even with compatibility adjustments. Would be really awesome to have the GOG team fix this up for Vista and 7 users. Plus DRM removal. :)

Every TES game up to Morrowind, that way I get a DOS compatible version I don't have to configure it and I can use a source port if I can locate one.
Area-51: I just like it, and the fact I need to use Internet connections to play my current copy (Add-supported version...) pisses me off since 20% of the time I have no signal or access.
The Chronicles of Riddick: Escape from Butcher Bay: Yeah, don't tell me this game sucked. We all know Vin Diesel is a way better video game avatar then an actor, and the brutality in this game is epic. Low res version preferred since I cant run the new version. =)

Not sure if it's been said yet (yeah i didn't want to search through all the pages...) I'd love to see some of the early Sierra games here, like Space Quest, King's Quest, Police Quest. Etc. I remember loving those games when i was a bit younger.

Battlespire and Redguard on GOG, that'd be awesome!

le bump

Add Raptor, Jazz Jackrabbit, and I'll buy them instantly.

I'd like Battlespire and Red guard too, would be really cool if some bethesda games were here.
Age of Mythology would also be sweet, really good strategy game.

Quake 1 + 2 + Quake III Gold Edition
Return to Castle Wolfenstein PLatinum Edition
Aliens Vs Predator 1 + 2
Clive Barker's Undying
Star Trek Voyager Elite Force 1 + 2
Half Life 1 + 2

Unfortunately, I don't think Valve would ever allow that to happen.