The problem starts when I install mods but I've always used these mods and I've never had a problem before till. I used a bunch of other fixes and tweaks on Planescape and that works fine now but I used to use the one from The Gibberlings 3 site and then it goes all down hill from there.

I'm wondering if the games are no longer compatible with the mods from The Gibberlings 3?

Clarify the following:
What is the base game and version.
Install this in a folder outside windows folders.
Run it, does it run fine?
Choose a mod, specify name of mod and version, and install it.
What is the output from adding the mod and does the game run then?
Once you have isolated a base game + mod which causes this issue then we can recreate it and see what is happening. Currently, you seem to already have a modded game so there could be any conflicts and such like.

Well I have purged galaxy off my pc and Arcanum works but still Icewind Dale 1 and Baldur's Gate 2 as soon are mooded won't launch. The list of Icewind Dale mods are:

Auril's Bane
One Pixel Productions Animation Fixes for IWD:TotLM:
The IWD Fixpack
One Pixel Productions
Icewind Dale Tweak Pack
The Widescreen Mod

The Widescreen works but as soon as I install the others it goes south =/

Also here's a pic of my process.

I found the problem was the 1pp mod.

Apologies, I had meant to get back to you on this, but I totally forgot. Glad you got it sorted. If you have problems, always a good idea to install one mod at a time. There can be problems in one mod, but also conflicts with mods.

No worries and thanks for your help. It is strange as I've never had a problem till now but I won't let it bother me too much. =)

I've been experiment with a few things and it turns out it was Avast was causing the problem. I've set it up so that makes an exception on my gog folder and boom everything is back to normal even the 1pp mod is installed =D