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So i'm going to at least try this.

BG2/ToB

1. Henchmen killed on sight when possible
2. Non plot lockers killed on sight after any mandatory conversation with the exception of vendors who may only be stolen from and then killed if they are not hostile already.
3. No mods or cheats
4. Plot lockers killed as soon as possible

CE Gnome Thief/Mage for just all the backstabbing. The fluffy reason is Irenicus' actions have made her mind snap so that she's convinced she's the avatar of Urdlen.

Any suggestions on particular courses of action, apart from *don't*?
Post edited May 28, 2017 by Malamis
One little tip: You can kill characters with HP1 items, but it is a little tricky. The easiest way to do this (that I know about) is stat drain. For this reason, the normally useless Contagion spell (which drains Strength and stacks) is very useful for this purpose. Add in Ray of Enfeeblement and you can do this with only 3 Contagion spells. Later, you can Shapechange into a Mind Flayer for easier stat kills.

I believe you can't kill the Irenicus Dungeon version of Imoen (the one with Imoen's Belt) unless you start as a pure Mage or Sorcerer; a multi-class Mage doesn't start at a high enough level to pick a 4th level spell, and for whatever reason the game does not let Mages pick spells at level up. (The Scroll of Weakness can help, as it acts like Ray of Enfeeblement on the user, but it can't finish the job.) Actually, on second thought, there *is* a way; skip the cutscene that occurs when you leave the dungeon (this is apparently quite tricky; you might want to look at information meant for speedrunners), get the Contagion spell (which apparently may require keeping her with you all the way to the underworld), and then kill her. (Or you could use Limited Wish to Shapechange, but that is a one-time only wish.)

Killing the tutorial guy I believe to be impossible without back-transferring a Throne of Bhaal level character, as the only way I have killed him is with (Greater) Deathblow. (I used cheats to test this.)

Also, killing certain plot important characters in one scene might not prevent them from appearing in another. For example, killing Imoen in Irenicus's Dungeon will not prevent her from appearing in the cutscene when you leave the dungeon.
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Malamis: Any suggestions on particular courses of action, apart from *don't*?
Don't bother trying to kill Imoen until you meet up with her again in Spellhold, because you WILL meet up with her again.

The rest can all be killed either on sight or right after recruiting them. Aerie: Refuse to give her the "key" (she will attack). Viconia: let the mob do it for you. Haer Dalis: don't bother freeing him. Valygar: go through with the assassination quest. Not much else to say other than your reason is very flimsy.
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Malamis: Any suggestions on particular courses of action, apart from *don't*?
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Hickory: Don't bother trying to kill Imoen until you meet up with her again in Spellhold, because you WILL meet up with her again.
Actually, from the perspective of the game engine, the Imoen you meet in Irenicus's Dungeon and the Imoen you meet in Spellhold are different characters; in fact, it is possible to get both in your party at once (skip the cutscene when she leaves, but play through Spellhold normally without skipping it). Note that reducing ID Imoen's HP will not kill her, as she has a minimum HP item and will leave your party (without dying) when she reaches 1 HP.

One other thing: In Chapter 2, you will most likely want to join Bodhi. If you side with the Shadow Thieves, or if you try to kill them before siding with Bodhi, you will have to contend with the strong version of Arkanis Gath, whose weapon has a guaranteed instant death effect, and who has a minimum HP item (so you can't kill him by conventional means). It *is* possible to kill him (except in the EE), but doing so will require a lot of trickery, especially without the Death Ward spell, so you are probably better off taking the choice that avoids the encounter entirely. (Once you side with Bodhi, you will instead encounter the weaker version of Arkanis Gath, who is realistically killable under ordinary circumstances, I believe.)

One more thing: If you don't want to have to resort to ridiculous tricks (including glitches and exploits), consider excluding characters with minimum HP items from the genocide rule, instead letting them live. This will avoid the need to have to resort to absurd strategies (like using a one-time Limited Wish to turn into a Mind Flayer).
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Hickory: Don't bother trying to kill Imoen until you meet up with her again in Spellhold, because you WILL meet up with her again.
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dtgreene: Actually, from the perspective of the game engine, the Imoen you meet in Irenicus's Dungeon and the Imoen you meet in Spellhold are different characters;
Oh, just shut up!
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Hickory: Oh, just shut up!
Is there a reason you feel the need to make such a rude and non-constructive post?

Anyway, back on topic:

It occurred to me that the rule against buying items with your money may prevent you from getting items that are needed to kill characters with minimum HP items, like the Limited Wish scroll.

One option might be to play a Sorcerer; this way you are not dependent on being able to find scrolls for the spells you need. If you can reach level 18, you can learn Shapechange, which is the easiest way to kill characters with minimum HP items; otherwise, you need to use Contagion. Unfortunately, you can't get Death Ward, so you will still have trouble with Arkanis Gath.

If you wish to kill Arcanis Gath (and not side with the vampires), I would suggest getting rid of the rule about not buying from shopkeepers so that you can actually get the items you need. Then, you can play a Cleric/Mage, which gets you access to Death Ward as well as the arcane spells you need. (Note that you can save Arkanis Gath until Chapter 6, and it is probably a good idea to do so.)

(Trying to post again because the post didn't show up the first time.)
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Hickory: Oh, just shut up!
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dtgreene: Is there a reason you feel the need to make such a rude and non-constructive post?
It was quite constructive: you bring nothing but off-topic nonsense to any discussion you enter, so your "back on topic" is totally meaningless. You never actually read the original post in any discussion, or if you do you purposely ignore the intent. It's no wonder people down-rep you continually.
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dtgreene: Is there a reason you feel the need to make such a rude and non-constructive post?
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Hickory: It was quite constructive: you bring nothing but off-topic nonsense to any discussion you enter, so your "back on topic" is totally meaningless. You never actually read the original post in any discussion, or if you do you purposely ignore the intent. It's no wonder people down-rep you continually.
That's incorrect. What I posted is on topic (the topic being killing every NPC in the game); what you posted is not and seems like an attempt to censor me, not to mention being rude.
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dtgreene: What I posted is on topic
No it isn't. The OP quite clearly stated: "3. No mods or cheats "

The problem is, you don't know the meaning of the word 'cheat'.

what you posted is not
You're quite clearly delusional.
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dtgreene: What I posted is on topic
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Hickory: No it isn't. The OP quite clearly stated: "3. No mods or cheats "

The problem is, you don't know the meaning of the word 'cheat'.
I do know the meaning of the word "cheat". Nowhere do I suggest using the cheat console or modifying the game with a save file or third party program. (Note that I do not consider taking advantage of bugs or flaws in the game mechanics to be cheating.)

I note that, if you don't allow the use of certain (arguable) flaws in the game (specifically the one regarding characters with minimum HP items being killable via stat drain), then the task is impossible as stated unless you side with the vampires (to avoid the powered up Arkanis Gath) and spare characters with minimum HP items.
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Hickory: No it isn't. The OP quite clearly stated: "3. No mods or cheats "

The problem is, you don't know the meaning of the word 'cheat'.
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dtgreene: I do know the meaning of the word "cheat". Nowhere do I suggest using the cheat console or modifying the game with a save file or third party program. (Note that I do not consider taking advantage of bugs or flaws in the game mechanics to be cheating.)
Thanks for proving my point.
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dtgreene: I do know the meaning of the word "cheat". Nowhere do I suggest using the cheat console or modifying the game with a save file or third party program. (Note that I do not consider taking advantage of bugs or flaws in the game mechanics to be cheating.)
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Hickory: Thanks for proving my point.
That reminds me when dtgreene did not consider using killsword cheating since it was already an ingame item. Which, you cant get unless you use the console.
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Hickory: Thanks for proving my point.
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Engerek01: That reminds me when dtgreene did not consider using killsword cheating since it was already an ingame item. Which, you cant get unless you use the console.
But... but the devs put it in! ;)
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Hickory: Thanks for proving my point.
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Engerek01: That reminds me when dtgreene did not consider using killsword cheating since it was already an ingame item. Which, you cant get unless you use the console.
I don't remember ever saying that. (Maybe you were thinking of the topic where I compared it to the EE's Story Mode, which, like the killsword, reduces the difficulty to 0.) Or, perhaps, the one where I suggested using it when testing a mod (specifically, for testing the scripting, not for testing battle difficulty).

By the way, the killsword is not capable of killing characters with minimum HP items, and the Ctrl-Y cheat doesn't work either.

Also, where's the OP?
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Perhaps he got tired of inane posts from the inkblot test.