First of all, i dont speak proper english, so i try my best, and i hope, you will understand me.

I try to explain the easiest way to play Worms on a Mac. I use a MacBook Pro with Yosemite 10.10.4 and i can play Worms very well.

First Step : Install "Wine" with "WineBottler"
winebottler.kronenberg.org

Download WineBottler and install just Wine. You can install WineBottler too, but its not necessary.

Secont Step :
Buy and download Worms from GOG

Third Step :
Start Wine and double click on the dowloaded file "setup_worms_united_2.0.0.20.exe". A window will popup. Choose "Run directly in..", press "Go". Install the Game. å

Fourth Step :
After installation, DONT run the game. Close the window and press on the little Wineicon on top right of your Screen and choose "File Manager". On the next Screen go to the Folder - "GOG games/Worms United" and double click on the file "Launch Graphic Mode Setup.Ink".

Fiftht Step:
On "Basic Settings" deactivate "Full Screen". If you run Worms in full screen, your Mouse will not work correctly. Choose the window resolution on "Advanced Settings", if you choose a "Scaling Engine", the game will look better but you cant choose a Window resolution. Just try out. Press "Save Settings" and then press "Start Game" .

At the beginning of the game just move your mouse a little bit around because some mouse issiuses, after a few seconds the mouse will work well.

Thats all. Have fun.