Awesome step-by-step instructions are at the "Cosmic Forge" forum, courtesy of "Krynn". GOG won't let me post links, so a cut-and-paste of his instructions are below:
Thought to update on this as I figure out how to get your editor work in Mac.
Step 1: Download and install Wineskin Winery from [GOG won't let me post the link! Try google. It's by Urges Software]
Step 2: Open the app and create an engine and make note of location of the engine.
Step 3: Download CF, unzip the .rar [Note - by "CF" he means the Mad God Cosmic Forge editor]
Step 4: Drag the unzipped folder into the engine icon.
Step 5: There should be new window pop up, it may take a bit for it to open, be patient. Double click on CosmicForgeU.exe
Step 6: Point the game installation path, this will vary depending where you get game from (Steam vs Gog for example). Since I got mine from Gog, the following files path is default:
Wizardry 6
Z:\Applications\Wizardry 6+7\Wizardry 6.app\Contents\Resources\Wizardry 6.boxer\C Wizardry 6.harddisk
Wizardry 7
Z:\Applications\Wizardry 7.app\Contents\Resources\Wizardry 7.boxer\C Wizardry 7.harddisk\DSAVANT
I don't use Wizardry 7 Gold, and don't have Wizardry 8 yet. But path should be similar.
Step 7: Use Editor as normal; however, make note that saved files are in different locations, again for Gog, the path is:
Wizardry 6
Z:\Users\<your username where game is installed on>\Library\Application Support\Boxer\Gamebox States\com.gog.wizardry-6\Current.boxerstate\C Wizardry 6.harddisk
Wizardry 7
Z:\Users\<your username where game is installed on>\Library\Application Support\Boxer\Gamebox States\com.gog.wizardry-7\Current.boxerstate\C Wizardry 6.harddisk\DSAVANT
Gold or Wizardry 8, don't have game yet but path should be similar.
Notes that I noticed, for Wizardry 6, Weapon Equip patch will not work as it will show Read Error, but all other patches can be applied. As for Wizardry 7, as version 4.19, all patches can be applied with no error. However, Attach to the Running Game feature will not work.
Cheers,
iiago