Im have a problem not being able to exit the nav screen. While in space, i hit 'N" key to pick my destination, the manual says to hit the 'Esc" button to exit nav screen, but it just locks up. Anyone else having this problem?

Sometimes I have to press ESC twice but I'll assume you've already tried that. When you say it locks up does that mean the entire game locks up, or that the other buttons on that screen still work but that you simply can't get out of the nav screen? Is this something that happens every time, or once in a while?

Its not my computer. I can move the nav point around by pressing 'N' and key strokes makes sound. Just cant exit the nav screen.

Hmm, maybe try clicking the Quad/Sys button (I think that's what it's labeled) twice, forcing the software to "rethink" the nav screen. Beyond that, I don't know what to suggest.