BananaJane: How do you run those? I get that error a lot with most of my games
Trying to run x32 on x64
If the installers are 16-bits the problem is with the installers. The game itself is 32-bits, but is using a 16-bit installer. The game itself would run under Win10x64 if the installer program is also 32-bits. But 16-bit installers were often used in Windows 9x (95. 98, Me), as these were hybrid 16/32-bit OSes. Win10x64 is a hybrid 32/64-bit OS, thus 16-bit programs of any description will not run, including 16-bit installers.
I would take the advice offered here and pay the $10-$15 depending on which games you want to buy, as the installer works on a 64-bit OS like Win10x64 just fine. Toss the disks away--you won't need them any longer. GOG specializes in doing the things it needs to do to get older games to run properly in up-to-date OSes. AFAIK, actually, Steam does not do the same, but sells the older original games it still lists in their original state, warts and all. At least, that was the way Steam worked last time I looked at an older game there--hopefully, they've changed that by now, but all I can say for sure is that you are safe with GOG in that regard.