Get it as usual from The Patches Scrolls:
https://patches-scrolls.de/patch/4647/7/74937

Changelog:

v10.1 30.09.2018
-----
+Fixed Gary giving packs if you already have some and made it plus.
+Shortened Bat's Communion to work with Beastmistress history too.
+Added Humanity gain for saving the quick Nosferatu in the warrens.
+Updated thin bloods on beachhouse beach and added monastery beds.
+Changed surplus Tremere history and improved Andrei's atrium exit.
+Restored billboard and Chateau computer and fixed Obfuscate info.
+Fixed Ground 0 Humanity losses and wrong basic poster quest email.
+Restored Arthur's computer and improved formats, thanks Psycho-A.
+Updated tutorial guard voice and SDK, thanks voerman and Psycho-A.
+Modified Chupacabra and Insectoid histories to avoid warform bug.
+Changed zoom factor of Steyr and SWAT rifle to real world numbers.
+Made Kamikaze Zen money stay in plus and Andrei don't drop braid.
+Some superfluous items can be given to Pisha, Skelter and Strauss.
+Made Carson quest more logical by having the player phone Gimble.
+Added male blood doll to Smoke Shop and a surprise to pier ending.
+Moved Knox in Asylum to restore lines of Cal and some for Arthur.
+Corrected Auspex stats if you use "no changed disciplines" option.
+Swapped final poster quest poster and restored it to Ground Zero.
+Restored partial damage to supernaturals with several disciplines.
+Updated some entries in some computers to reflect NPC fatalities.
+Fixed four Humanity cost altering histories, thanks miracle.flame.
Made CDC guy at Fu Syndicate unbiteable like the others downtown.
Prevented player from using idle animation during a few cutscenes.
Added info to hacking popup and fixed minor map and text details.
Fixed condition for telling Damsel that you killed a werewolf too.
Changed criminal level of several weapons to get police to react.
Repaired small issues in warrens and hospital maps by recompiling.
Fixed critical bug when talking to Zhao from the shelves outside.
Unified formatting of newspaper articles and improved GUI details.
Added toilet doors to a few maps and fixed minor dialogue issues.
Fixed Presence hair and cleared Disciplines before more cutscenes.
Covered level holes in observatory, Red Dragon and Venture Tower.
Fixed vanishing details downtown, at Ocean House, and in cemetery.
Added missing monster sounds reacting to Dementation disciplines.
Made the patch copy all bin files into main folder to fix crashes.

Additional changelog for RC2:

+Removed plus and extras installer sub-options to avoid confusion.
+Improved snatching cutscene and made museum outside a combat area.
+Fixed an ignoring-Sabbat-ending issue and sneaking out with Kiki.
+Made Hengeyokai not freeze on Blood Theft and fixed Ji quest loop.
+Improved library and made Red Spot gum ball machine destructable.
Moved breakroom at the SM clinic so the geometry fits the outside.
Made blood dolls reappear after killing to avoid staying corpses.
Moved sarcophagus loading scene to Giovanni mansion back entrance.

Additional changelog for RC3 which also is the 10.1 final:

+Finally fixed the dead-dog-still-hurting and Milligan freeze bugs.
Made sure beachhouse thugs are dead if Mercurio appears at beach.
Disabled bad icons and buttons for inactive Ocean House elevator.

Which mods is this compatible with? For that matter, which mods are compatible with each other? Its not very clear.

Only model, texture and sound mods can be mixed with major projects like the UP, TFN, CQM, ATM or others. But all install in their own subfolders now, so they can be run in parrallel from one Bloodlines installation...

Cheers, wesp5.

I notice that there will be a new CQM. Will that come with your latest patch?

Not yet. But it will be updated to the latest patch once both are stable...

Here is the RC2: https://patches-scrolls.de/patch/4647/7/74934

Additional changelog:

+Removed plus and extras installer sub-options to avoid confusion.
+Improved snatching cutscene and made museum outside a combat area.
+Fixed an ignoring-Sabbat-ending issue and sneaking out with Kiki.
+Made Hengeyokai not freeze on Blood Theft and fixed Ji quest loop.
+Improved library and made Red Spot gum ball machine destructable.
Moved breakroom at the SM clinic so the geometry fits the outside.
Made blood dolls reappear after killing to avoid staying corpses.
Moved sarcophagus loading scene to Giovanni mansion back entrance.

Thanks for yet another release! Still going through an 10.0 run so it'll probably be full release 10.1 before I get to try it though.

Definitely glad to see the installer options reworked, since they were giving me a headache every single time I installed a new version (even though I knew exactly what the options meant (including due to past experience), it still did my head in for some reason).

BTW what's the "snatching cutscene" and how does it relate to outside of the museum?

Also BTW, you're probably aware that virus checkers (Avast in particular) keep going nuts when downloading your patch (since at least 9.something), and the only way to get it to download required temporarily disabling Avast's shields - not an ideal solution. Maybe there's some way to submit the file to Avast's servers so they stop flagging this as a potential threat? Unfortunately since I can't download it without disabling the shields, I don't get an automatic option to submit it via Avast itself. I do allow it to do its (laborious) scan after the download, but that always comes up clean (so again no option to submit to Avast).

Both are not related but I tend to merge changes in one line to make the readme shorter. The snatching cutscene is the one in the warrens where the spiderchick snatches a guard... I know about this but I don't know the reason why. There are some files used in the SDK that might trigger a false alarm and there is also the suspicion that The Patches Scrolls site is too small and therefore flagged as insecure, but this is not my site...

This is cool, I'm about to start a game for the first time.

How do I install your patch, Wesp? And which things should I include for a first playthrough?

(I also saw that there is an unofficial patch on terra-arcanum, but I don't know if that is yours)

The patch comes with a self explaining installer and you can either choose the default basic patch which only includes bug fixes or the plus version which restored a lot of lost and unfinished content including several new maps! I would suspect that this is for Arcanum, another game by Troika...

Hi, was playing the game with this patch version. Got stuck after the boss fight of 2 chinese brothers. I spawn right outside of the main entrance gate and nothing happens. Im basically out of bounds.

The cutscene with truck doesnt trigger.

This is a known problem with RC2. Please download RC3, install it on top and try again. If it doesn't work, try from a save before you went to the mansion...

With a save file right before the mansion, everything worked. Thanks for your help, kudos.

wesp5, is there any news on when this patch will be here?

Are you keep in touch with GOG staff since the previous patch release?

Yes, I tell them when the final version is done, but I don't know if they intend to update to each new version...