DieRuhe: I was about to start up Bloodlines last night and then thought, you know, it's far past time that I've gotten Redemption so I got it last night. Haven't gotten very far, but they are quite different beasts. Amazing that there was only a four-year span between them. Redemption is definitely more old-school, but I think it's safe to say that I'll love it.
Redemption does have its charm to it especially for those who can make the game work on their computer. But a couple of other things people can think about is that 1) Redemption has far more variable mods than Bloodlines (that even includes whole new quests, items, and enemies) and 2) A working multiplayer though you have to use a VPN client these days like tunngle to get that to work.
I can actually tell that a lot of modders for Bloodlines are reaching an impasse on what more they can do with that game. Much of the Bloodlines community is hoping for the completion of the Project Valderie that will port Bloodlines to the Unity engine. On the other hand it looks like modders for Redemption have just started up on whole new content again for the original game. You can check it out here:
http://e-mods.net Among that website's content, I would highly recommend the Age of Redemption mod as it does some awesome things to the single player game which includes improving the AI, fixing several bugs, modifying some quests, and adding new disciplines like Obtenebration, Movement of the Mind, and Quietus.