meilers3: I have the exact problem. Windows 7 Professional, Nvidia 460 GTX, AMD 8-core 4.0GHz, 8 GB of RAM. Will not run in XP compatibility mode, nor in Administrative mode. Extremely disappointing.
Signothorn: So the game completes the install without errors, correct? This could be a bik issue, more people have been having that problem lately. Might try replacing the binkw.32.dll file with the one from Elder Scrolls Oblivion, or making sure there is no software, windows or bios settings that mess with cpu throttling.
Thanks for your suggestions. I have already tried the rename .bik files trick, but I have not tried replacing them. I get the message "Vampire.exe has stopped working" and then the screen re-sizes to desktop size, and then it quits.
I don't understand exactly what you mean by CPU throttling - I have an 8-core AMD CPU and that seems to have issues with older software (or vice versa) - I had a hell of a time getting TA and TA:Kingdoms to run, and I still can't get Sacrifice to run at all (even in Win XP compatibility). What would interfere with throttling?