I spent a lot of time last year trying to run the game but the game just won't run.Tried installing several times,checked youtube and searched a lot on google but couldn't find a fix anywhere.I have spent a few HOURS today as well but the game just won't work.Here's what I've found now though.There's a log file in the game directory named goglog.ini and it has the following text:

[1207659179]
Regs=2
ValueName_0=Executable
RootKey_0=HKEY_LOCAL_MACHINE
SubKey_0=Software\Eidos\Total Overdose
ValueType_0=string
ValueData_0=TotalOverdose.exe
ValueName_1=InstallDir
RootKey_1=HKEY_LOCAL_MACHINE
SubKey_1=Software\Eidos\Total Overdose
ValueType_1=string
ValueData_1=c:\total overdose//
Dirs=1
Dir_0=C:\Users\USERNAME\Documents\Total Overdose

Strangely there's no Eidos or Total Overdose registry key in the registry when I checked.Maybe that's the problem?

[EDIT : Switching monitor to 60 Hz from 120 Hz solved the issue after spending hours and hours on other things.The game apparantly doesn't run on higher refresh rate displays.]