Hi

After completing missions in Moreau lab (the one that gives you mutations) i enter the portal leading out and game start loading, then after 5-8 minutes states I died and suggest I have to reload save. There is loading sign on black screen, and no disk activity.

Tried redownloading and reinstalling entire game, no help, still stuck.

Any ideas?

Yes, yes, sure.

If you didn't use any cheats, mods, scripts etc. in your playthrough leading to your actual savegame then upload the save and give us the link.

Else your savegame may be corrupt.

Does it load an earlier save?