Finally have a bit of time to play this awesome game but unfortunately I'm now at an impasse...

I'm on the Kayran quest and I've just collected the ostmurk and created the atidote, but now when I try to return to Flotsam, no matter which entrance I use, the game suddenly crashes to desktop.

It seems kinda similar the problems reported here

http://www.gog.com/en/forum/the_witcher_2/serious_crash_to_desktop_problems_since_flotsam/

but a couple of differences. First I'm running win x64 so the 3gb trick doesn't make any difference for me. Second I can stay in the forest for as long as I want, it only crashes when I try to return to Flotsam.

Also it seems that it's only a problem for my current save. If I load an older one I can go in and out of flotsam freely...

Any one got similar problem / solutions?

Thaks!

See if lowering your Texture Memory Size will help. Set it to small/ or very small :)
That fixed it for me in 32bit windows... However now i'm with 64bit cuz of this game and those crashes are gone. Odd thing that you're with x64 and you have random CTD in Flotsam.

Just tried setting everything to minimum, but still crashes, however it did take a second longer than before.

I would say they're not random crashes either. The only happen when I go through one of Flotsams doors. If I run around the forest it remain very stable.

Replayed to the same point from an earlier save and now it seems fine! Must have been a corrupted save file I guess... My advice everyone save often and don't rely on quicksave!

Hmmm, spoke to soon. It's now crashing when I hack of a Kayran limb...

I'm having the exact same problem. I've got 17 hours played in the game without a single problem at all. Today (after installing 1.1) every time I try to get near Flotsam I immediately crash to deskop. I haven't made any other significant changes to my system, so I'm wondering if this isn't an issue introduced by the patch?

Either way, game is now unplayable as I kind of need to be able to get into Flotsam.

(Running Windows 7 x64).

Hopefully there's a solution out there?