Welcome to the world of irritation =/ Seems we're both with the 6950's, so be sure to tell us if anything happens that gets it working for you ;)

Trying a ground-up reinstall again here, updated everything on the comp just to be safe.

I have the same exact problem as well. I have the 6850 card.

I have an HD4890 and have the same problem.

I had the same problem: Radeon HD 5770, updated to Catalyst 11.5 yesterday.
But the solution was fairly simple: simply check "use application settings" in Catalyst Control Center: voilà, everything looks fine now.

EDIT: Not saying this will work for everybody, just for people like me who were absent-minded enough to forget about this...

Can't verify as I don't have them xfired, but on the official site there was a post that you have to disable crossfire and run it on one card only, that should fix the corruption.

I had the same issue and can confirm that this fixed it for me.

I'm Stuck with the Wolf Logo and nothing happening!! going to reset the comp..
p.s. I had a virus on the witcher.exe
Special detection TR/Dropper.Gen

Description:
A generic detection routine designed to detect common family characteristics shared in several variants.

This special detection routine was developed in order to detect unknown variants and will be enhanced continuously.

was going to verify this fix, but now i cant get the game to launch, it just stays on the Witcher Medalion and that is it, just stays there forever. Any fix for this?

I can confirm that updating to Catalyst 10.5 and turning on Use Application Settings fixed the issue for me.