Browse to the folder where the game is installed. There are over a thousand files in that directory, but you should be able to find the file feeble.ini. Open it in wordpad. (It won't display correctly in notepad because it uses Unix-style line breaks, but wordpad should work)
Find the following line:
fullscreen=true
and change it to:
fullscreen=false
Save the file and launch the game. It should now run in a window!
Edit: I found that the game runs in a very small window (640x480) and it isn't resizable. Here's how to enlarge the window:
Open feeble.ini again. After the very last line, insert this new line:
gfx_mode=2x
save and close the file.
Before it will work though, you must update ScummVM, the virtual machine that the game runs inside of. Go to
http://scummvm.org/downloads.php and download the "Windows zipfile" release of the newest ScummVM version (0.13.1 at the time of this writing).
Inside your Feeble Files folder there should be a subfolder called ScummVM. Extract your newly downloaded version of ScummVM here, this should overwrite some of the existing files.
Now the game will run at twice the previous window height and width, i.e. 1280x960.
If your monitor is
really huge, you could insert gfx_mode=3x in the config file. This will triple the dimensions instead of doubling them, i.e. 1920x1440.