I managed to install and run The Pandora Directive in Boxer on the mac. It runs perfectly. The method may work with the other games in the series since they also run via DOSBOX, but I have not tested it. It is a bit of a walkthrough, but - hey - you are installing a Tex Murphy game.
First, you need to run the installer. If you already have it installed on Windows just grab the game folder from there, if not do it through WINE. I used Wineskin, installed the newest engine (WS7Wine1.3.16, but it shouldn't matter for this) and the latest wrapper (Wineskin-2.1). Create a new blank wrapper, call it 'Pandora', run it, click 'Install Windows Software' and run the Pandora Directive installer from GOG.com.
Once the game is installed, right-click on the 'Pandora' wrapper in the Wineskin folder and select 'Show package contents'. Open the Pandora folder in drive_c/Program Files/GOG.com. Copy the file dosboxtex4.conf to your desktop.
Download and install Boxer, if you don't already have it. I used version 1.0. In Boxer choose 'Import a game' and drop the Pandora folder from before in the window and name it 'The Pandora Directive'.
Now locate the imported game in the 'DOS games' folder, right-click it and select 'Show package contents'. Then create an empty folder named 'D.cdrom' there.
Rename dosboxtex4.conf on your desktop to 'DOSBox Preferences.conf' and copy it to the folder replacing the old file.
Now the game runs from Boxer and you can delete the Pandora wrapper in the Wineskin folder.
UPDATE: Since The Overseer does not run through DOSBOX it is not possible to run it in Boxer, but Under A Killing Moon does work with the same method. Instead of creating an empty 'D.cdrom' folder, add the letters F, G, H and I in front of each of the .iso files. E.g. F UAKM1.iso, G UAKM2.iso etc.
Post edited April 02, 2011 by bieder