Deimos_Fresh: Well, from my experience playing both fully patched CD versions of original SC and FA, both will crash regardless how many AIs you use. I remember reading that AI in both have flawed script and I think no support for multi core CPUs is also responsible for crashes in skirmish mode.
Opportunity for an experiment! Create a virtual machine with Windows 10 installed (just let it be un-activated F the desktop image customization) and set the machine to have just a single processor. If it still crashes, then maybe the AI script--are the AI scripts viewable? Event Viewer may provide a clue.
From the sounds of it, it's been crashing its whole life...I wouldn't know. I've never played it but bought it and am about to return it to wait for a Steam sale for FA:Forever. Just lurking around here to see if there happened to be any success with FA:Forever & GOG version. Saw the multi-core CPU speculation and couldn't just walk away knowing how that hypothesis could be tested to either a solution to the problem or a reduction in dimensionality of the problem