This is a head-scratcher. ZRP makes things run better, normally. The game with ZRP uses less memory than the normal game by itself. Make sure you are not using any compatibility mode. Also try limiting your framerate to 250 or less in your video driver's configuration tool, especially if you have a relatively-recent computer. Using your monitor's preferred refresh frequency is recommended.
Do you have cloud saves enabled? I don't recommend this; if your game or computer crashes, there can be loss of access to all the saves online. And this feature might be slowed down by some interaction with your game using ZRP.
Also, if you have loaded any new features that GOG now supplies (example: the removal of the requirement to give permission to launch the game every time you try to start it -- a good idea), there may be some new incompatibility with ZRP introduced by the changes.
Check to see if any software is running in the background that might interfere with the execution of the game. GOG Galaxy should not cause problems, but the game can be run in standalone mode by downloading a backup copy from GOG, installing this backup copy (not to Program Files! -- see below) and then running the game. It might be that your antivirus is constantly checking the ZRP files as they are loaded during the game's execution.
I don't know what you mean by "unpacked the gamedata directory in the SoC folder". If you didn't just copy over the gamedata folder from the extracted ZRP archive, then I'd suggest removing the gamedata folder and trying again. If you installed to "C:\Program Files (x86)\", then I don't recommend using ZRP or any mod with that installation location, as it is for protected program and system files, not for user modification. There may be issues with UAC or
Volume Shadow Copy, AKA Virtual Store.
That's what I've got to start. If I think of anything else, I'll reply again.