I'm tempted to say you're missing out if you don't go out and do things at night. Also the way it can make things feel different is worth keeping in mind if replaying. Did a mission during the day last time? Try doing it at night this time.
I especially like outdoor monster related things at night, hearing things running around in the dark around you is great fun.
edit,
Started replaying Shadows recently, just got to the Clear Bloodsucker Village mission in the middle of the night and the guys there gave me another mission to kill the Bloodsuckers so it turned into a two for one. It was quite fun, being dark and raining with night vision it looked like there could be a one just about anywhere especially when a dust cloud moved somewhere. Every now and then you'd hear one growl and one smashed it's way out of a house as I was sneakily approaching the entrance for a nice little random jump scare.
It's one of the nice things about the game, the way day and night can change things so much, go in guns blazing during the day or sneak in at night trying to off a few Bloodsuckers before they all start going crazy. Anyway, up way to late again because of this but still great fun.
Post edited July 14, 2015 by Grogger