The first time I played, I got to the point I left the apartment. I got the leve transition screen, with the brain in the corner and that was it, it got stuck on that part forever. I had to go to the task manager to shut the game down. I started a new game, and got to the place where I'm supposed to have the scan. Door's locked. "I can figure this out". And then I can't so anything. I'm stuck at that spot. I can't move, can't click on anything. My vision gets blurry, I'm guessing from the tracer fluid? But that's as far as it gets. No verbal clues or anything. I feel like I get a little further each time but it seems like something is wrong. The game seems really interesing and I'd love to play it.
Win 10
8gb ram
i7 6700 3.4 ghz
GeForce GTX 980 Ti 6GB

Very strange - I only had one crash during my full playthrough!
And I probably played for 15-20h, since I like to take my time and enjoy the great athmosphere :)