I just installed Sim City 3000 on my new computer. When the game loads up, the image of my cursor doesn't line up where the cursor actually is. I see the cursor on the screen, but it's able to click on something about an inch and a half southeast of the physical image of the cursor. I didn't have this issue with Sim City 3000 on my previous computer and I've tried reinstalling the game to no avail. Any advice is much appreciated.

I had this problem with the mouse too.

Use my guide to get the game running using DxWnd.
DxWnd has a built-in framerate limiter that will mostly fix the main problem. And if you want you can follow the extra steps to make the UI/fonts look bigger on the screen.

https://www.gog.com/forum/simcity_series/fixed_these_problems_using_dxwnd_map_scrolling_speed_high_cpu_usage_small_textui/page1