YanniFirewind: Since there's currently no manual for the game, can anyone provide me some basic advice on how to play the game and not be terrible? (And/Or a PDF of the manual?)
Start a game on the easiest setting. Immediately start breaking into places and taking photos / bugging things / shooting people / chucking grenades.
Seriously - play through at least one madman-style spree to learn the controls, especially during the building infiltrations. Mess up a few wiretaps / vehicle tracking submissions.
Wiretapping will provide information over time, assuming you target the right buildings. Infiltrating a building before you're ready to take out its occupying agent can get hairy - raise the alarm and it'll be heavily guarded when/if you come back. On the flip side taking photos of desks and wall safes is maybe the quickest way to get information. If an agent for a particular group is active in an area then target that building, obviously (if you know where it is). If you're completely lost try targeting the buildings of the primary group even if you're unsure which cities their group is being active in.
Green grenades are gas. Red are fragmentation (lethal). White are concussion.
During the infiltration missions, or when you are ambushed, the numberpad controls your movement. 5 toggles walk and crouch - you can crouch to avoid detection. So can they once they're aware of you (grenades are your friend at that point). The regular arrow keys make you leap in that direction, which stops your movement for a second but lets you cross over furniture and ends in a crouch. If you are facing a visible enemy a crosshair appears in your picture - slap FIRE when this happens. I think a white crosshair is a guaranteed hit.
You win when you capture the mastermind. You lose when the plot is completed. The middle ground is preventing the plot but allowing the villain to escape. During the post-op investigation there's usually a clue or two as to the mastermind's identity that gets discovered - the most sure but least exciting method of winning is quickly taking out a critical link in the plot and then waiting for things to wrap up. Done a handful of times this'll eventually allow you to target the Mastermind directly. But it is more fun trying to figure it out while on the case than letting the post-op team handle the intel gathering.
Combat tips : Don't throw gas grenades if you're not wearing a gas mask. Sounds obvious, but it happens. Consider booby-trapping funnel points like doorways after the shooting starts (F10). Always take the vest. You can get grenades mid-mission by shooting the guards, so they're usually safe to leave behind (unless you're going in hot to take out a predetermined target and don't care about getting any information) The headphones let you hear when enemies are in adjacent rooms and might even be more important than the vest. You can throw grenades through doorways. The enemy will do the same. Gas grenades will take out an enemy before he crosses a room, but not before he shoots you full of holes - use it to temporarily close off the rooms they need to travel through to get to you. Gas is more about area denial than straight offense. Touching an enemy will kill them and do one damage to you. Even with the vest you can just take four or five shots - if they hit you with a concussion grenade they'll usually stroll up and take you out before you get your breath.