I'm getting constant crashes with the game.
Without warning, the game will crash to desktop and throw an "Fatal Error!" without any further information.
Sometimes I can play for 30-40 minutes, sometimes I crash every minute. Some places seem more crash-prone than others. E.g. I crash every other time when entering the backroom in Mrs. Ninis'
I tried playing in fullscreen and windowed fullscreen, DX11 mode as advised by the devs, run as administrator.
No issues in other games.

Any advice what to do?

System:
AMD R5 5600
AMD RX 480 8GB
16GB Ram
Win 10 Pro