I switched to "mini galaxy" to handle my GOG games collection and it works very well. I noticed it updated my Shadowrun HK version that was on a hiatus for a while.
I decided to get back at it today, only to discover the game is completely silent, whatever I do... quite disappointed.

Upgrades to Ubuntu 20.04.4 seems to have "cleaned" deeply some "useless" 32 bits libraries. Running following command (again) in a terminal fixes the problem:

sudo apt-get install libc6:i386 libasound2:i386 libasound2-data:i386 libasound2-plugins:i386 libstdc++6:i386 libx11-6:i386 libxau6:i386 libxcb1:i386 libxcursor1:i386 libxdmcp6:i386 libxext6:i386 libxfixes3:i386 libxinerama1:i386 libxrandr2:i386 libxrender1:i386 libglu1:i386