We all know how scarce are karma points. So usually player had to get his nose right into anything. Here are the two things I can't get to in my 1st mission (deliver a message):
1. There is a woman who sells clothes. She claims that she wasn't paid for the ordered suit and asks you to bring it up upon meeting with your *friend*. No special dialog option here. Same with you?
2. There is a closed door in lower levels, can't be decked out, don't have a code. Have you?

The closed door in the north-west of the lower levels can't be decked, but you can get the code from a spirit off to the side of the Lotus Den entrance on the rooftops level. Requires you to bring Gobbet or have Spirit Summoning 2. I got 1 Karma and 60-65 Nuyen (seems random, different whenever I reload) for opening it and defeating the dogs within.

Edit: The spirit's in an alley nearby, to the east of the Lotus Den and the guards blocking its entrance. It's really easy to miss.

Thanks a lot!

I stumbled onto several bugs with "lost" dialog options. For example you can inquire medical clinic owner about some stuff for riggers and get a reference to a vendor, but if you reload a game just before that and do the same thing you may realize that there is no such option anymore. The same goes with dialog option regarding AR googles (level 3 deck). Somehow the game applied future dialog check onto your previous save data file.
Perhaps option for unpaid suit was poorly coded.
Due to various typos in dialog (some words repeated twice) I'm afraid beta testers weren't interested that much. Sigh.

Thanks for the info about simsense recording. I was sure to sell it to a fixer like I did in Shadowrun Returns; now I know it just magically whisked away from my pockets.
I also noticed that Auntie gave me 2 memory sticks to deliver, but after a while it also disappeared. I've got a hole in jacket.

After a long hunt I finally came to realise that is the door with the 'red graffiti'... I didn't see no 'red graffiti' :/ The 'nearby'; part was also a bit misleading.

One place I was surprised that I got no reward was upon returning to the student to inform her I had finished the repairs... I got nothing at all, not even the satisfaction of my efforts being worthwhile.

I didn't see the point of that quest at all.

Not completely true. You get +1 karma for actual completing this optional quest (3 stages), informing her is a way to unfold a gruesome plot.

Sorry mate. I accidentally misclicked a different post as a solution. My bad. It can't be undone now. You got a +1 from me and +1 karma from universe ;)

You see I was actually on the look out for this and I did it twice just to make sure.. I didn't get a reward, I did the three parts and reported back.. No karma given.

I knew what I was looking for I wouldn't have posted this if I was wrong... However now I have to put it down as a bug instead of it being an unrewarded quest in general.

Impossible! Though I believe you. I got +1 karma after fixing wires using my intellect, then extinguishing tires on fire with a bucket of sand, then downstairs turned the valve using Duncan because I had no strength. Then I got +1 instantly.

I also got +1 for taking back old man's credstick; and nothing for giving it back to him. So the no reward from her after last conversation was okay for me.

I will start a new game and check this in different order. I playing a charismatic elf and told a scholar that I know about qi and that she should stay there I'll get all fixed (3rd dialog option).

Was wondering why I got marked as the solution...
I'm pretty sure I got +1 karma after I completed the last of the 3 tasks for that quest, so turning it in doesn't give you anything extra.

The credstick thing was the same for me. Apparently taking it is worth karma, giving it back isn't. Considering I like to be at least a little bit of an asshole in Shadowrun, I was okay with this. :)

I didn't notice +1 karma after repairing the wires with INT specifically though, but I could have just missed it.

Who said that? You get +1 karma only after you complete all 3 tasks.

"I got +1 karma after fixing wires using my intellect, then extinguishing tires on fire with a bucket of sand, then downstairs turned the valve using Duncan because I had no strength"

Sorry, guess I misinterpreted what you wrote. I guess since you followed up that sentence with "Then I got +1 instantly", I took this to mean you got +1 from the wires and then another +1 from all three.

By the way, karma isn't so scarce in this game. You can max out your main skills by the time you reach the final third of the game, and then you'll be putting points into other skills just to spread out your abilities a little. It's money that's really tight – as a decker, I could only afford the best deck and armor for my character, with a program or two thrown in every now and then. Buying consumables or upgrading my followers' equipment was out of the question.