At the point where you want to hire Runners for the first time from Mr Delilah: "Yeah. I'm ready to go. Let's see 'em."

After that, the Seamstresses Union goes dark, but can still be seen in the background. The music and the mouse pointer are also still there, but the hiring screen for selecting runners is not displayed. You can no longer do anything.

I then tested it with the Steam version and it works.