I'm not very swift with computers, but when I open this game, everything appears to have shifted to the left and I lose about 15% of the screen. Having no luck trying to run it in windowed mode as that just crashes the program. Any help would be greatly appreciated.

I haven't got a clue, but perhaps you should contact gogsupport, maybe they will find your problem mighty interesting.

I'm having the same issue. The game crashes if I mess with any compatibility settings. I'm experimenting now to see if I can fix it.

I'm running Win 7 64 bit at 1920 X 1080 resolution. Do you have something similar?