Hello,
Couldnt find any solution so I'm trying here. When I'm trying to lunch risen 2 game starting but the screen showing only half game window which flashes and is full of graphic artifacts that make game unplayable. I'm using Windows 10 and radeon 580, tryed to install latest PhySx driver but nothing has changed also tryed to run it with win7/xp compatibility and with truned off all radeon driver settings. Really wanted to play this game, hope you will help me somehow.

Could you please check at which resolution is the game running? For instance, in your monitor's menu. In AMD Settings, do you have Virtual Super Resolution turned on? If yes, try to turn it off. Also, check there if GPU Scaling is turned on or off.