RawSteelUT: You know? I wonder why the whole Jill Easy thing was added to the PC version to begin with. I don't remember people complaining about the difficulty level for Jill back then, and giving her the two extra item slots seemed like a huge buff in and of itself.

Wild.Dog: Jill was easy mode on the original PSX version too. She has more ammo, she has her handgun at the start, she has more slots for stuff. The lockpick lets you open locked drawers to get more stuff while with chris you need to waste a slot with a small key.
Barry gives you ammo quite often, you can get the shotgun early since barry will open the door and rescue you if you don't use the broken shotgun.

Homekill: Right it's not just the lack of ink ribbons. On your first run all the enemies are weaker like zombies will die in around 3 or 4 handgun shots instead of 6 to 7

AydanWatkins: It is possible, but you need to modify a file in the DATA folder. Open up BIOCARD.DAT in a hex editor, edit the byte with the new value shown in the attachment and just hit save. That way every time you start a new game it will be at the correct western difficulty that we had on the original PlayStation release, where Jill has to use Ink Ribbons and enemies take a few more bullets / do more damage etc.

I've attached an image showing the exact value and what to change it to. Enjoy a much better and authentic experience!

I've been modding RE1 for so long that it's like a second home to me.