Whenever I go to save my game I get an error message about a problem occurred and I should try saving over an old save (which I am typically doing anyways, which is bad form in a Sierra game). If I try to change directory for the saves, it keeps telling me any folder I try is no good. Anyone know a fix for this, as I don't want to uninstall/reinstall and maybe lose my old saves, but not a problem if that's the only way.

You can always just copy the save directory before uninstall/reinstall. What OS, where is the game installed to and are you running it as administrator?