Going with a Fighter->Paladin (no thief skills) and a Magic User->Wizard (who also has thief skills) would cover [i]
most[/i] of the series content in two play-throughs, but you'd still miss out on the thief-class-specific portions of QFG3, and couldn't do all three endings of QFG2 (unless you play the end sequence multiple times with the mage/thief).
With a single character? An all-skills paladin would be able to see a reasonable amount of the game but would miss out on the thief-specific content of #2 and #3, and could not access most of the wizard-related material in #3, #4, and #5. He would likewise only be able to access certain end sequences in #2, and undertaking the thief missions in #5 would prove awkward due to the Honor hit.
Likewise, certain marriage options in #5 would be blocked off with either of these approaches.
Three play throughs (as Fighter->Paladin, Magic User->Wizard, and Thief) without cross-class skills (to be on the safe side) are necessary to see everything. (There is only one thing that the Fighter can do and the Paladin can't, which is marry a certain character in QFG5 - but the Wizard can marry that one as long as he doesn't have the Lock Picking skill.)
Post edited January 16, 2013 by Garran