FGogS: It does seem to have a few issues, though.
Some Sprites (?) don't work correctly, for instance, the mouse cursor has its square around it being shown when you move it, flickering. It should be invisible, normally. Also, the desktop will be visible under the game in spots now and then.
I also had the game not reacting when you move the cursor to the screen's edges which should normally move the screen around the map.
Few other issues now and then, basically, it's kind of a pain to play it like that. Wish it would be a bit better optimized for Win8, especially with touchscreens. I mean, this sort of games is perfect for touchscreen controls, but, of course, the game is like a hundred years old and Win8 only newborn, so we can't really expect too much.
Do you have multiple GPUs? That sounds similar to issues the game has when there's more than a single GPU running. You can force it to run with a single GPU.