I'm on the Mac version and have encountered an issue where my characters will walk towards a selected interactable item but will not loot corpses or open chests. Is anyone else facing this problem or have an idea of how to counteract it?

It sounds like this bug: http://forums.obsidian.net/topic/71947-bug-cant-pick-items-from-containers/

I have this problem too. Thanks VanishedOne for pointing to the official forums link. I submitted some logs to the devs there and hopefully they can figure something out because my disappointment right now is beyond extremely unbearable. Been waiting two and a half years for this game only to have a game breaking bug from the very very beginning!