What's the pros and cons with the original and the remake? If I, who haven't played the game, should play Pathologic for the first time. Should I get the original or the remake?

Hard to say exactly what the pros and cons are as the remake won't be out until next year. The remake will almost certainly be prettier from what we've seen thus far and there's no reason yet to believe that it won't be good, but no-one can say that for sure until it's released. On the other hand, the original is dirt cheap right now and a very good, if weird, game. Also note that the remake won't be a beat for beat copy with prettier graphics, but more of a reimagining - a different interpretation of the same story - so if you play one of them it's still worth playing the other as well, as there's enjoyment to be had from contrasting them and seeing what they do differently.

I would recommend getting the original Pathologic to see how you like it, unless you want to play the remake with absolutely no foreknowledge of the plot whatsoever or strongly dislike the dated graphics, and then play the remake as well when it comes out. If you definitely only want to buy one of them, wait until the remake is released to see what people say about it.

It's still sort of unclear where this a remake, remagining, or sequel. What is clear, however, is that Icepick Lodge aren't changing their ways regarding misery inducing gameplay and design. Pick up Classic HD in a sale, if you don't like it, you certainly won't like the upcoming game.

Ok I see. Well I'll probably get the HD version then when it hits sale. So there are no reason to play the vanilla version before the HD? Since both are available to buy I mean.

As far as I know, the main difference is the translation. The vanilla translation being quite a bad one and HD making much more sense to an English reader.

Ok cool. Thanks for everything :) Yeah I'm gonna get the HD when it's on sale next time, thanks :)

Good timing, It's on sale right now. :P

And yes, there's no reason to start with the original over the Classic HD version. The Classic HD overall has a better English translation, some restored content and runs better as well. You can always play the original afterwards because you'll get it for free anyway for buying Pathologic Classic HD. You'd only want to do that though if you want to experience the original script, which becomes much more comprehensible if you play the HD version first, as they're otherwise the exact same game.

I don't know if it's just me, or original game and hd version have a difference in balance? I'm talking about item balance, for example, the original game gives me hardly any resources, I hardly know what would I get from the trashcan, or what would I get from a drunk man in water bottle exchange. But in the hd version, I found a broken watch in 6 or 9 different trashcans all around the city, and every single one of a drunk man had only bandages and not a single tow...
Did something like this happened to you too?

I rarely find anything better than an empty bottle in trashcans, so I don't think they changed anything. The game can be pretty random when it comes to good finds though, like some houses being filled with goodies and others having only trash.

I feel the same about game but it seems like there is some math and numbers behind it. Maybe game changes loot in trashes and houses at new walktrough? I mean like it's preety hard to survive in this game, and what would you find in trashes and houses is matters, it almoust decide will you live or will you die) at least that how i felt last time playing)

I started playing this on my older laptop but the HD version was running poorly, so I went for the original. I think I was at around day 4-5. After I got to my desktop, I switched to the HD.
You definitely find more stuff in the HD. Not only is there more stuff in containers, there's also less empty containers. For example, in HD, you'll almost always have more water than there are bandages for trade. Some changes to prices have been done as well I think. And later on, you have so much different stuff from containers that inventory space becomes an issue even during bachelor campaign.

GAMEPLAY SPOILER:
If you're having problems with supplies, here's two tips: Hoard as much stuff as possible and spend all your money on day 1. Sell everything for massive profit on day 2. The game even hints on multiple occasions that you should do it. Don't sells scraps other than razors or other expensive ones. They're worth more as trade items still (technically, so are razors, but you're not always able to "spend" it's worth in trades).

Once arsonists start appearing (day 6), you want to have a rifle (get it earlier) and buy as much ammo for it as possible (Bad Grief has a bunch every day). Each arsonist carries more money than a rifle bullet costs and they also carry some aditional supplies, so it is profitable to kill them, not to mention effortless and quick (altough their death animation is painfully slow). Also remember that revolver ammo sells for more money than rifle ammo (despite being cheaper in trades with kids), so make rifle your primary firearm and when you need money, sell revolver ammo.
END SPOILER

Either way, I would recommend the HD classic because of the better translation. At first, some dialogues in the original just seem weird, but eventually you'll get to sentences which are completely unintelligible and you may not even understand certain plots because of it. So I would certainly recommend playing the HD classic.