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After update I was unable to teleport effectively back to my home base. Funky graphics and would not let me leave the main room. Tried to relocate base but that simply lost everything. Tried to build new base because my blueprints were all missing. Scientist in my new lab gives me nothing. Over 100 hours into this game and now zilch. Have no intentions to restart.
Reports are few so its most likely very very isolated.

100hrs in a game like this is f'k all, one thing I do know is that you will play again.