I've gotten crashes when I quit the same, or around explosions.
i.e. I had an item that makes my weapon explode after traveling a short distance, another to help me shoot fast. Add them together = a lot of boom on targets that are tanky.... which results in crash.
I had other times a bullet spreads and crashes... Maybe too much happening on the screen for unity to handle? or not well optimized.

edit:
Team17 asked me to do a repair on the game, I did so but still crashing around explosives. It was on a god tier run, about to fight athena and unity crash. I will give them 1 more week before requesting refund.