I understand that this is a common issue for vista users, and I have tried various fixes which include: downgrading quicktime, adjusting quicktime settings (safe mode etc), editing myst compatibility settings. None of these fixes have worked or even improved the situation. So I'm hoping I've missed something obvious and can finally play Myst!

I am running on vista 32 bit, 2gb ram, 2.2 ghz graphics.
I should have mentioned that this is Myst Masterpiece Edition if that helps.