SpellSword: ...I seem to remember Myst using it, ...
Yes and you can get the newest version of Quicktime here:
http://www.apple.com/quicktime/download/ If you're still experiencing video problems, try this:
In QuickTimes control panel change the video mode to "Safe mode (GDI only)"
You find QuickTime's control panel in your system's Control Panel => QuickTime (on 64-bit Windows you must click the "View x86 Control Panel Icons" button on the left side of the Control Panel window before the QuickTime icon appears)
If this doesn't fix your problem, you can try using an older version of QuickTime (uninstall the current one before)
GOG provides a download for
QuickTime 6.52.
To set "Safe Mode" in QuickTime 6 look in the Video Settings section in the drop-down menu of QT.