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Umm placed his ashes in the large room, cause didn't read the clue well enough and it was the large room at the back or the door mazes. I know where it has to go. The urn is invisible but shows when you use wizard eye, an I can't pick it up. Will I be able to get another urn latter or is there some way to pick up this one.

Another problem is that I have drained the minotaur lair and found the trapped minotaurs but its still flooded in all the houses and shops when I come back, so the are some skill levels that I can't gain.

I also have found no way to the Regnan Islands, although this may be because I have not finished the urn quest and bought a witness to the lake of fire back to Alvan.

Any help much appreciated

so glad these games didn't die with makers and glad ubisoft has nothing to do with them
This question / problem has been solved by MalcolmMasherimage
If you lose a quest item, you can say "I lost it" to the Seer near Ravenshore and he'll give you a new one. You may have to repeat this a few times, since Vilebite's Ashes won't necessarily be the first thing he gives you, but hopefully he'll cough it up.

I think you have to kill all the enemies in Balthazar Lair before it can be repaired, which can be annoying because some of them go underwater? It's been a while. I'd suggest checking the area thoroughly with Wizard Eye.

You won't be able to go to Regna until the plot directs you to do so.