I just purchased the game for nostalgic reasons (enjoyed the PS1 port and always wanted to try the PC version). I'm definitely liking the game here, but I wish I could rebind the keys on the keyboard so I don't have to cramp up my hands. Is there some way to rebind the controls from the arrow keys to WASD?

Unfortunately, there doesn't seem to be any in-game option to do so. In Dungeon Keeper you could rebind them to anything.

Anybody know of a way to do this using the DOSBox config file?

I actually addressed this question in an unrelated topic: here

If I may add, simply reassigning cursor values to WASD keys didn't work for me. What I had to do to make those keys work, is to reassign unbound WASD keys to cursors too, so no letters were missing from the keyboard. I ended with LEFT/UP/RIGHT/DOWN bound to WASD and WASD bound to CSR LEFT/UP/RIGHT/DOWN. Only after that it worked.

YES! The free program I use is called AutoHotkey, it works wonders for all types of games to rebind or to set the controls for the keyboard or make macros to perform many actions! Download autohotkey and install, open up the autohotkey.ahk file they give you in my documents to see how it looks. Read the help file of the program and learn to REMAP keys. I made my mouse button 4 = 20 clicks of the regular left mouse button, so now I have instant auto fire. I might change it to 40 clicks. Here is simple instructions, 1. download and install autohotkey, 2. open notepad, 3. type this XButton1::Click 40 then 4. save the file on your desktop as click40.ahk then 5. exit notepad, 6. double click the ahk file on your desktop to load it on your system tray. 7. anytime you press mousebutton4 u will get 40 clicks, 8. play your game, 9. right click on H icon in your system tray and read the help file to make more! Anyway, Autohotkey is a must have for any computer owner, gamer or not.