I know there isn't much information on this problem, since it's quite surprising, but I can't seem to get scummvm to actually launch Lures of the Temptress.
Even using the default INI that the GoG installer offers, it looks like it fails after trying to load the actual game itself.
A copy of my lure.ini file (as seen in Notepad++) [NOTE: All backslashes were removed by the GoG forums]
[scummvm]
music_volume=192
midi_gain=100
speech_volume=192
browser_lastpath=
aspect_ratio=false
music_driver=auto
lastselectedgame=lure
native_mt32=false
subtitles=false
fullscreen=false
sfx_volume=192
talkspeed=60
speech_mute=false
autosave_period=300
enable_gs=false
multi_midi=false
versioninfo=0.12.0
[[lure]
description=Lure of the Temptress (VGA/DOS/English)
midi_gain=100
path=C:Program FilesGOG.comLure of the Temptress
aspect_ratio=true
music_driver=windows
native_mt32=true
subtitles=true
extra=VGA
platform=pc
gameid=lure
language=en
fullscreen=true
talkspeed=60
speech_mute=false
enable_gs=true
multi_midi=true
savepath=C:Program FilesGOG.comLure of the Temptress
Other Scummvm games like Beneath the Steel Sky seem to work just dandy.
Attempted Solutions:
*Launch LURE via BASS' installation of scumvm
->FAILED (Same Result)
*Reinstall LURE
->FAILED (Same Result)
*Redownload LURE installer
->FAILED (Same Result via GoG Downloader)
I'd of course like to see if others are having issues other than me.. I guess I just prefer to try and solve issues on my own prior to contacting GoG's support groups. (Especially for a free game, I mean come on, the least I can do is try to troubleshoot my end right? ;) )

I'm probably entirely missing the point of this thread but my copy of "Lure of the Temptress" runs perfectly well when I click on the shortcut kindly supplied free by GOG

Hehe, well - the point of the thread is that it does not on Freyar's hardware.
Never had any problems with any ScummVM titles myself, either.

I do apologise if my post came over as a bit smug, it certainly wasn't meant to.
I have messed about with (and messed up) computers many times and more often than not found that the fault was usually down to something so obvious and trivial that a self inflicted kick up the behind was required after piecing together the wreckage!!
I sincerely hope that this particular problem is soon successfully resolved.
Regards.