triock: Well, this is for PC version, but my guess is that it's the same for Mac.
The “arrow keys” allow the player to move Twinsen. The movement depending of the “behavior mode” will be a normal walk, fast run, angry-slow walk, and slow-discreet steps.
The “Space Bar” allows the player to perform an action depending on the “behavior mode” selected
The “Alt key” is used to attack with the current weapon selected.
The “Control key” shows the current status and behavior mode: life bar, magic bar (once the 1st level is reached), number of coins, number of keys and clover boxes (empty or containing a clover). You can change the behavior mode from here by holding the Control key and moving with the left and right arrow keys.
“Shift key” brings the inventory. You can move around it with the arrow keys to read the descriptions. Long descriptions can be continued by pressing Space Bar. You can use the items with Enter.
“Enter” centers the camera on Twinsen.
“H” will open the Holomap as soon as Twinsen gets it.
F1-F4 are quick keys to change behavior modes.
F5 zooms the image.
F6 opens the Option Menu.
Just as a heads-up, if OP is using a Macintosh keyboard, the function keys (F1-F6) may only work via the "fn" modifier. So if OP wanted to use the quick key to change to the normal position, then the keypress "fn+f1" would be used. Otherwise, OS X's hotkeys will be used when F1-F6 is pressed even in-game.