In Poisonville (second level) I was sent by Louie to get something out of the safe in the Blanco warehouse. When I finally reached it there was a key on the table which I distinctly remember picking up. I loaded the game a bunch of times while trying to get the power off (the safe is behind an electrified face), and when I finally got to it I couldn't get the safe open, and there is no key in my inventory.
Has this been known to happen, or did I break new ground here?

Thank you! For some reason Louie didn't mention the demoguy or the safecracker until i went back to the club and talked to him. You have my deepest gratitude.