In most cases, IWD:EE should run without issues. However if you are running hardware which uses open-source / MESA graphical drivers, you may encounter issues with white/black background and non-visible buttons/feature in the UI.

In case of no textures, try to force using S3TC texture compression (if available by your driver):

in terminal, navigate to your installation directory and run:

force_s3tc_enable=true ./start.sh

Alternatively, you can install system library that replaces S3TC:

yum install libtxc_dxtn
(install for x32 and x32_64)
(it should be called something like this in Ubuntu "libtxc-dxtn-s2tc0" )

If you are still having problems, check the terminal log for this kind of errors:

"
Running Icewind Dale Enhanced Edition
libGL error: unable to load driver: r600_dri.so
libGL error: driver pointer missing
libGL error: failed to load driver: r600
libGL error: unable to load driver: swrast_dri.so
libGL error: failed to load driver: swrast
INFO: Creating DPWrapper
"

In that case, navigate to you installation folder ~/Icewind Dale Enhanced Edition/libs/ and delete or rename file:
libstdc++.so into libstdc++_.so

After that, IWD:EE should run normally.

Thank You. This also helped me on my 64bit debian/bunsenlab instalation.

I've added this info to the wiki:

https://www.gogwiki.com/wiki/Infinity_Engine#Linux

I already knew about the libstdc++.so issue (I had to use it myself to get the game to work ever since it came out), but didn't know that the S3TC issue (which affects many Linux games) also affect this one since I always have libtxc_dxtn installed anyway.