When I attempt to replay the main game of GL3 The Dark City, I find myself having a problem zooming in to the ticket booth from the first area. The first time I tried repeating, it wouldn't let me zoom in at all. I deleted the profile and played it through fine. The next time I tried to repeat it, It won't let my zoom in a second time to use the lock-picks on the lock.

Did you catch one of the hidden objects (the little skeletons that fade in and out of sight) in that zoom area? If you catch one that you already got in the first playthrough, there's a bug that doesn't let you zoom in to that area afterwards. I encountered this myself in the starting area of the game.

That bug is known since 2016 and still not fixed appearently, although one of the devs said on Steam that they'll "look into it pronto". Alas, they didn't, or at least not for the GOG version. :(