Does anyone else had this problem? The game runs fine (60+fps), fully patched to CP 1.75, but when I try to apply any kind of reshade of sweetfx on it, the fps plummets to 15-25 and doesn't really recover. I've tried several versions of reshade, even going back to older Sweetfx version, but nothing works. It's a shame because reshade would really help this game.

Can anyone help with this? I have an AMD Radeon RX 570 GPU, could that be the problem?

I am on Windows10 and I have the same problem.
I last played it on WIn7 several years ago and I think that it wasnt as bad as now then (but my memory can be misleading, of course).
Do you play on Win10?