DA:O Awakenings
Fallout New Vegas
Alpha Protocol
Already picked up Fallout 3 GotY (got it at a discount, so grabbed it).

update:
removed C&C 4

Risen
Divine Divinity 2 (with the expansion pack!)
Fallout New Vegas
Age of Decadence (is it Thursday yet?!?!)
Zombie RPG .... not going to happen this exact year but hey...
Drakensang: River of Time

update:
removed:
Borderlands
Dawn of Discovery: Gold Edition
looking forward:
more casual games

Civilization V Instabuy
Football Manager 2011 Instabuy
Just Cause The moment it drops below €20 (demo without timelimit will do for now)
Empires of Steel The moment it drops below €20 (never worth the initial pricetag of $45 methinks.

Meh,i can't edit the title of the thread :(
So,the new title
"Your game wishlist for 2010 - 2011"
update for my list:
- Rage

There is only one game I will get no matter what, as I have it pre-ordered. Money is restricting my other purchases, but I still want the games. And I will get them eventually if they turn out to be good.
Will buy:
Red Dead Redemption (X360)
Want:
Dead Rising 2 (X360)
Fallout: New Vegas (PC)
Deathspank (PC)
Mafia 2 (PC)
Deus Ex 3 (PC)
Portal 2 (PC)
Mario Galaxy 2 (Wii)
New Zelda (Wii)

Starcraft 2
Civilization V
World of Warcraft: Cataclysm
Will see if I have time to play anything else if I don't want to lose my job

Yeah... I have to move Rage to a 2011 list, and Doom 4 for 2012-13. :p
Don't know if Max Payne 3 and Delta Force are still coming out in 2010, too.
People here will hate this, but I will add COD7: Black Ops to my list, since I've liked the trailer and I like the Vietnam setting. I will judge it when it arrives.
Already got Amnesia:TDD, but I've never heard about this Darkness Within series, now I'll look for it.
Thanks, Namur.
Too bad Alan Wake will never be out for PC, and EP3 will arrive only in 2017.
I want some console games too, but I don't own one. So I won't bother listing console exclusives. :(

MAFIA 2
That's really the only thing I can think of that I really want this year.

Updated the list. No more Ubisoft games for me except on GoG. Also, my Dad has a PS3, so I'll be getting GoW 3

Games I hope will be good for the remainder of this year:
Alpha Protocol
Mafia II
Arcania
Deus Ex: Human Revolution
Fallout: New Vegas
FEAR 3
How many of these I get on PC has yet to be seen, as it depends on the DRM.

I prefer to avoid wanting things, especially games, because I've been disappointed too often in the past. (It's also cheaper this way! ;-) )
But this looks awesome enough, and it's indie, so it shouldn't get fucked by a publisher...so, yeah, I'll probably pre-order it pretty soon.
Achron

Updated list 2010.05.23
non GOG releses :
Rage
Telltale Games releases :
The Secret of Monkey Island 2: LeChucks Revenge: Special Edition
GOG releases : ( current wishlist )
Empire Earth 3
Enclave
Psychonauts
Outcast
Master of Orion 1+2
M.A.X. + M.A.X. 2
Blood 2: The Chosen + Expansion
Master of Magic
One unit whole Blood
Divine Divinity
Beyond Divinity
Empire Earth 2 Gold Edition
Call to Power 2
Caesar 3
Mob Rule
Constructor
removed:
The Operational Art of War III
John Tiller's Campaign Series
War in the Pacific: Admiral's Edition

Dead Rising 2
Naughty Bear
The Last Guardian
All that comes to mind.