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Mine would have to be:
1. Binding of Isaac
2. Spelunky
3. Super Meat Boy
4. Breath of Death VII
5. Legend of Grimrock
6. Jolly Rover
7. Lone Survivor
8. Cthullu saves the World
9. Trine
10. Dwarf Fortress

I defiantly know that VVVVV would have been on that list had I the full game but as it's a demo, it's not really fair to judge but it's a brilliant game anyway.
1: Grimrock
2: Tiny and big
3: World of goo
4: Trine
5: Nikopol (not sure if indie though)
6: Machinarium
7: Botanicula
Post edited December 07, 2012 by gameon
1. Bastion
2. The Walking Dead
3. Sam and Max: Season 3
4. LIMBO
5. To The Moon
6. Blackwell series
7. Sam and Max: Season 1
8. Braid
9. Gemini Rue
10. The Binding of Isaac


note: there are alot i haven't played (Primordia or Resonance) - but so far the list looks like this for me.. and i really doubt a game will shake up the top 5 any time soon..
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McDon: Mine would have to be:
1. Binding of Isaac
2. Spelunky
3. Super Meat Boy
4. Breath of Death VII
5. Legend of Grimrock
6. Jolly Rover
7. Lone Survivor
8. Cthullu saves the World
9. Trine
10. Dwarf Fortress

I defiantly know that VVVVV would have been on that list had I the full game but as it's a demo, it's not really fair to judge but it's a brilliant game anyway.
Aquaria
Brogue
Treasure Adventure
Spelunky
Driftmoon
Hotline Miami
Cave Story
Torchlight
Inquisitor
Dwarf Fortress
1. Faster than Light
2. Zafehouse Diaries
3. Dwarf Fortress
4. Recettear (Indie?)
5. Gnomoria
6. Towns
7. A Game of Dwarves
8. Terraria
9. Minecraft

I obviously need to stop buying Indies since I can barely think of 10 I played to any decent amount of time >.<
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darknath: 2. The Walking Dead
3. Sam and Max: Season 3
Telltales is Indie? O_o
Post edited December 06, 2012 by Pheace
Dungeons of Dredmor and Terraria. The best of the best. Lone Survivor and Binding of Isaac are pretty cool too. Also, I really adore SpiderWeb Software games.

Oh, and To The moon for the story and characters.

PS. LIMBO sucks.
Post edited December 06, 2012 by keeveek
in no particular order

Jamestown
Super Meatboy
Binding of Issac
Dungeons of Dredmor
Primordia
La Mulana(both versions)
Legend of Grimrock
Terraria
Cthulhu Saves the world
Bastion
My top 10 favorites:
Cave Story
Treasure Adventure Game
The White Chamber
Torchlight
Hotline Miami
Alien Shooter 2: Reloaded
Starscape
Excelsior: Phase Two - Errondor
Escape Velocity: Nova
Survival Crisis Z
Not a specific order, but off the top of my head.

Cave Story
Escape Goat
Bastion
Legend of Grimrock
Trine
Frozen Synapse
Jamestown
Torchlight
Symphony
Beat Hazard
1 - Call of Duty
2 - Half Life 2
3 - Settlers 7
5 - Assassins Creed
6 - Skyrim
7 - Unreal
8 - Portal 2
9 - Borderlands
10 - Splinter Cell

(What's an indie game? trollface)
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amok: 1 - Call of Duty
2 - Half Life 2
3 - Settlers 7
5 - Assassins Creed
6 - Skyrim
7 - Unreal
8 - Portal 2
9 - Borderlands
10 - Splinter Cell

(What's an indie game? trollface)
http://indianajones.wikia.com/wiki/List_of_Indiana_Jones_video_games
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Pheace: Telltales is Indie? O_o
its hard to see them that way with all the big IP's they've been involved with, but i believe they do fit the definition technically.
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amok:
(What's an indie game? trollface)
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gameon: http://indianajones.wikia.com/wiki/List_of_Indiana_Jones_video_games
lol +1, best definition so far.
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amok: 2 - Half Life 2
8 - Portal 2

(What's an indie game? trollface)
I've seen people defend Valve as indie among other things. (The only company that cares about it's customers was my favorite.) So those games appearing on someone's list seriously wouldn't shock me.
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darknath: 2. The Walking Dead
3. Sam and Max: Season 3
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Pheace: Telltales is Indie? O_o
Was about to say the same thing, if they're indie I'd have added a Sam and Max to my list :)